While your body ages, it begin changing with your bodies own pace. But how your body will be aged it depends in some part on your genetics, various diseases and mostly on your life style. Fortunately you can control your life style! Aging bring along some changes on your body which is common.
Now the researchers have invented a way to find out ageing cells across a wide range of biological materials; the new method will boost understanding of cellular development and ageing as well as the causes of various diseases.
Annoying by the limitations of commercially available biomarkers - researchers led by The University of Manchester’s Professor Paul Townsend and senior author of the resulting paper, and honorary professor at Manchester, Professor Vassilis Gorgoulis, have developed a universally applicable method to assess senescence across bio medicine, from cancer research to gerontology.
This new study finding has been published as ‘Robust, universal biomarker to detect senescent cells in biological specimens’ in the journal “Ageing Cell” and has led to two pending UK patents.
The Cellular senescence is a fundamental biological process involved in every day embryonic and adult life, both good and for natural human development and more importantly to researchers, dangerous by triggering disease conditions. Up to now available senescence detecting biomarkers have very limited and burdensome application. Therefore, a more effective, precise and easy-to-use biomarker would have considerable benefits for research and clinical practice.
“The method we have developed provides unprecedented advantages over any other available senescence detection products – it is straight-forward, sensitive, specific and widely applicable,even by non-experienced users”, says Professor Paul Townsend.
“The method we have developed provides unprecedented advantages over any other available senescence detection products – it is straight-forward, sensitive,specific and widely applicable, even by non-experienced users,” adds ProfessorTownsend.
“In addition to helping researchers make significant new breakthroughs into the causes of diseases – including cancer – through more effective understanding of senescence in cells, the new process will also aid the impact of emerging cellular rejuvenation therapies.
“By the better identification – and subsequently elimination of – senescent cells,tissues can be rejuvenated and the health span extended.”