“Although other studies have offered evidence that cannabinoids might be neuro-protective against the symptoms of Alzheimer’s, we believe our study is the first to demonstrate that cannabinoids affect both inflammation and amyloid beta accumulation in nerve cells,” said senior author David Schubert.
The researchers found that high levels of amyloid beta were associated with cellular inflammation and higher rates of neuron death. They demonstrated that exposing the cells to THC reduced amyloid beta protein levels and eliminated the inflammatory response from the nerve cells caused by the protein, thereby allowing the nerve cells to survive.
Schubert emphasized that his team’s findings were conducted in exploratory laboratory models and that the use of THC-like compounds as a therapy would need to be tested in clinical trials. Only time will tell if the medical marijuana finally give positive result in treating Alzheimer.